Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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Experiments
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[Homology]
Score
SPO1810Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (594 aa)    
Predicted Functional Partners:
SPO1809
nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027; match to protein family HMM PF00571; match to protein family HMM PF03445.
 
  
 0.985
SPO1811
Hypothetical protein; Identified by similarity to GB:CAE09733.1.
 
    0.969
SPO1808
Hypothetical protein; Identified by similarity to GB:AAD22393.1.
 
     0.896
SPO1807
Exonuclease, DNA polymerase III, epsilon subunit family; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573.
 
   
 0.835
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.677
adk-2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
     0.553
SPO1959
acetoacetyl-CoA synthase; Identified by similarity to SP:Q9Z3R3; match to protein family HMM PF00501; match to protein family HMM TIGR01217.
  
  
 0.430
acsA
Acetyl-coenzyme A synthetase; Identified by similarity to SP:P39062; match to protein family HMM PF00501.
  
  
 0.430
prpE
propionate--CoA ligase; Identified by similarity to SP:P77495; match to protein family HMM PF00501.
  
  
 0.430
badA-1
Benzoate-coenzyme A ligase; Identified by similarity to GB:AAA92151.1; match to protein family HMM PF00501.
  
  
 0.430
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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