| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO1820 | cpdA | SPO1820 | SPO1176 | Sugar ABC transporter, periplasmic sugar-binding protein; Identified by similarity to SP:P10904; match to protein family HMM PF01547. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.622 |
| SPO1820 | cpdA-2 | SPO1820 | SPO1819 | Sugar ABC transporter, periplasmic sugar-binding protein; Identified by similarity to SP:P10904; match to protein family HMM PF01547. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.854 |
| SPO2469 | SPO2904 | SPO2469 | SPO2904 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 0.904 |
| SPO2469 | adk-1 | SPO2469 | SPO0507 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.906 |
| SPO2469 | adk-2 | SPO2469 | SPO1812 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.906 |
| SPO2469 | amn | SPO2469 | SPO3745 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.900 |
| SPO2469 | apt | SPO2469 | SPO3066 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.903 |
| SPO2469 | cpdA | SPO2469 | SPO1176 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.900 |
| SPO2469 | cpdA-2 | SPO2469 | SPO1819 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.900 |
| SPO2469 | purB | SPO2469 | SPO2305 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.902 |
| SPO2469 | surE | SPO2469 | SPO2688 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.908 |
| SPO2904 | SPO2469 | SPO2904 | SPO2469 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.904 |
| SPO2904 | adk-1 | SPO2904 | SPO0507 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.903 |
| SPO2904 | adk-2 | SPO2904 | SPO1812 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.903 |
| SPO2904 | amn | SPO2904 | SPO3745 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.906 |
| SPO2904 | apt | SPO2904 | SPO3066 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.914 |
| SPO2904 | cpdA | SPO2904 | SPO1176 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.907 |
| SPO2904 | cpdA-2 | SPO2904 | SPO1819 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.907 |
| SPO2904 | purB | SPO2904 | SPO2305 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.911 |
| SPO2904 | surE | SPO2904 | SPO2688 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.911 |