Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPO1862metFprotein-like protein; Identified by similarity to PIR:B97532. (309 aa)    
Predicted Functional Partners:
SPO1863
Pterin-binding enzyme domain protein; Identified by match to protein family HMM PF00809.
 
 
 0.995
SPO1884
Identified by match to protein family HMM PF02574.
 
 
 0.969
SPO0635
Aminomethyl transferase family protein; Belongs to the GcvT family.
 
 
 0.947
SPO1861
Hypothetical protein; Identified by similarity to GB:BAB48658.1.
 
    0.943
glyA-1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.927
glyA-3
Serine hydroxymethyltransferase; Identified by match to protein family HMM PF00464.
  
 
 0.927
SPO0564
Aminomethyl transferase family protein; Belongs to the GcvT family.
 
 
 0.926
SPO0544
Aminomethyl transferase family protein; Belongs to the GcvT family.
 
 
 0.925
SPO1628
Identified by match to protein family HMM PF01266; match to protein family HMM PF01571; Belongs to the GcvT family.
 
 
 0.925
gcvH-1
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
 0.918
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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