| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0847 | SPO2013 | SPO0847 | SPO2013 | Non-ribosomal peptide synthetase; Identified by similarity to GB:CAC01603.1; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR01733. | Membrane protein, putative. | 0.575 |
| SPO0847 | pyrG | SPO0847 | SPO1312 | Non-ribosomal peptide synthetase; Identified by similarity to GB:CAC01603.1; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR01733. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.467 |
| SPO0847 | rimM | SPO0847 | SPO3255 | Non-ribosomal peptide synthetase; Identified by similarity to GB:CAC01603.1; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR01733. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.540 |
| SPO2013 | SPO0847 | SPO2013 | SPO0847 | Membrane protein, putative. | Non-ribosomal peptide synthetase; Identified by similarity to GB:CAC01603.1; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR01733. | 0.575 |
| SPO2013 | SPO2980 | SPO2013 | SPO2980 | Membrane protein, putative. | Porphyromonas-type peptidyl-arginine deiminase family protein; Identified by match to protein family HMM PF04371; Belongs to the agmatine deiminase family. | 0.457 |
| SPO2013 | ndk | SPO2013 | SPO2444 | Membrane protein, putative. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.401 |
| SPO2013 | putA | SPO2013 | SPO3010 | Membrane protein, putative. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.403 |
| SPO2013 | pyrG | SPO2013 | SPO1312 | Membrane protein, putative. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.445 |
| SPO2013 | rimM | SPO2013 | SPO3255 | Membrane protein, putative. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.445 |
| SPO2013 | rplD | SPO2013 | SPO3824 | Membrane protein, putative. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.410 |
| SPO2013 | rpsJ | SPO2013 | SPO3826 | Membrane protein, putative. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.417 |
| SPO2013 | speA | SPO2013 | SPO0602 | Membrane protein, putative. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. | 0.457 |
| SPO2013 | trmD | SPO2013 | SPO3259 | Membrane protein, putative. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.433 |
| SPO2980 | SPO2013 | SPO2980 | SPO2013 | Porphyromonas-type peptidyl-arginine deiminase family protein; Identified by match to protein family HMM PF04371; Belongs to the agmatine deiminase family. | Membrane protein, putative. | 0.457 |
| SPO2980 | speA | SPO2980 | SPO0602 | Porphyromonas-type peptidyl-arginine deiminase family protein; Identified by match to protein family HMM PF04371; Belongs to the agmatine deiminase family. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. | 0.928 |
| ndk | SPO2013 | SPO2444 | SPO2013 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Membrane protein, putative. | 0.401 |
| ndk | pyrG | SPO2444 | SPO1312 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.943 |
| ndk | rplD | SPO2444 | SPO3824 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.807 |
| ndk | rpsJ | SPO2444 | SPO3826 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.964 |
| ndk | trmD | SPO2444 | SPO3259 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.419 |