| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO2053 | SPO2056 | SPO2053 | SPO2056 | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | Thiamine-phosphate pyrophosphorylase, putative; Identified by similarity to SP:P39594. | 0.537 |
| SPO2053 | ctaA | SPO2053 | SPO2054 | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | 0.869 |
| SPO2053 | fabJ-1 | SPO2053 | SPO2920 | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | Fatty oxidation complex, alpha subunit; Identified by similarity to SP:P77399; match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | 0.416 |
| SPO2053 | pepF | SPO2053 | SPO1413 | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | Identified by match to protein family HMM PF01432. | 0.476 |
| SPO2053 | rho | SPO2053 | SPO3894 | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.417 |
| SPO2053 | trmJ | SPO2053 | SPO2055 | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.749 |
| SPO2056 | SPO2053 | SPO2056 | SPO2053 | Thiamine-phosphate pyrophosphorylase, putative; Identified by similarity to SP:P39594. | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | 0.537 |
| SPO2056 | ctaA | SPO2056 | SPO2054 | Thiamine-phosphate pyrophosphorylase, putative; Identified by similarity to SP:P39594. | Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | 0.552 |
| SPO2056 | trmJ | SPO2056 | SPO2055 | Thiamine-phosphate pyrophosphorylase, putative; Identified by similarity to SP:P39594. | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.657 |
| ctaA | SPO2053 | SPO2054 | SPO2053 | Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | 0.869 |
| ctaA | SPO2056 | SPO2054 | SPO2056 | Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | Thiamine-phosphate pyrophosphorylase, putative; Identified by similarity to SP:P39594. | 0.552 |
| ctaA | trmJ | SPO2054 | SPO2055 | Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.749 |
| fabJ-1 | SPO2053 | SPO2920 | SPO2053 | Fatty oxidation complex, alpha subunit; Identified by similarity to SP:P77399; match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737. | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | 0.416 |
| pepF | SPO2053 | SPO1413 | SPO2053 | Identified by match to protein family HMM PF01432. | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | 0.476 |
| rho | SPO2053 | SPO3894 | SPO2053 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | 0.417 |
| trmJ | SPO2053 | SPO2055 | SPO2053 | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. | 0.749 |
| trmJ | SPO2056 | SPO2055 | SPO2056 | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | Thiamine-phosphate pyrophosphorylase, putative; Identified by similarity to SP:P39594. | 0.657 |
| trmJ | ctaA | SPO2055 | SPO2054 | RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | 0.749 |