Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
psuGIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (304 aa)    
Predicted Functional Partners:
SPO2060
Kinase, pfkB family; Identified by match to protein family HMM PF00294.
 
  
 0.953
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
    
 0.909
SPO1777
Identified by match to protein family HMM PF00037; match to protein family HMM PF01180; match to protein family HMM TIGR01037.
  
 
 0.908
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.907
SPO1776
Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF00070.
     
  0.900
SPO2806
Cytosine deaminase, putative; Identified by similarity to SP:P25524.
     
  0.900
SPO2062
Hypothetical protein; Identified by similarity to GB:AAQ61403.1; match to protein family HMM PF04367.
  
    0.700
SPO2059
Identified by match to protein family HMM PF02798.
  
    0.605
SPO2058
Hypothetical protein; Identified by similarity to GB:BAC89701.1.
       0.572
SPO2063
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
       0.558
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (34%) [HD]