Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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SPO2103Antioxidant, AhpC/Tsa family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (182 aa)    
Predicted Functional Partners:
SPO3383
Thiol-specific antioxidant protein; Identified by similarity to GB:BAC00970.1; match to protein family HMM PF00578.
   
 0.841
SPO2104
Hypothetical protein; Identified by similarity to GB:AAK22261.1.
 
     0.558
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
     
 0.513
SPO2101
Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891.
       0.491
SPO0331
Thiol:disulfide interchange protein, putative; Identified by similarity to SP:P43221.
   
 0.454
SPO2314
Periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Identified by match to protein family HMM TIGR00385.
   
 0.454
SPO1084
Hypothetical protein; Identified by similarity to GB:CAC41724.1.
   
   0.422
SPO1192
Hypothetical protein; Identified by similarity to GB:AAK24936.1.
   
   0.422
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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