STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO2147Hypothetical protein; Identified by similarity to GB:CAC47284.1; match to protein family HMM PF05962. (174 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
       0.773
SPO2145
Hypothetical protein; Identified by similarity to PIR:T46851.
       0.762
hutC
Histidine utilization repressor; Identified by match to protein family HMM PF00392.
 
  
 0.714
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.688
SPO1369
Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392.
 
  
 0.687
hutG
N-formylglutamate amidohydrolase; Identified by match to protein family HMM PF05013; match to protein family HMM TIGR02017.
 
    0.680
hutI
Imidazolonepropionase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR01224; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
   
 0.657
hutH
Histidine ammonia-lyase; Identified by similarity to SP:P21310; match to protein family HMM PF00221; match to protein family HMM TIGR01225; Belongs to the PAL/histidase family.
 
  
 0.617
hutF
Formiminoglutamate deiminase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR02022.
 
    0.609
SPO2144
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.
       0.529
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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