Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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pdhCPyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (437 aa)    
Predicted Functional Partners:
SPO2222
Pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase, putative; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
 0.998
pdhA
Pyruvate dehydrogenase complex, E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.998
pdhB
Pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
0.996
acoB
Acetoin dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780.
 0.995
lpdA
2-oxoglutarate dehydrogenase, E3 component, dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
 0.994
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.
 0.989
SPO0585
Dehydrogenase/transketolase family protein.
 
 0.983
gltA
Citrate synthase I; Identified by similarity to SP:P00891; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.
  
 0.972
acoA
Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676.
 0.966
sucC
succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.932
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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