| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0833 | SPO1555 | SPO0833 | SPO1555 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | 0.999 |
| SPO0833 | nnrD | SPO0833 | SPO2293 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.726 |
| SPO0833 | sdhB | SPO0833 | SPO0361 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | Succinate dehydrogenase, iron-sulfur protein; Identified by match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.989 |
| SPO1150 | SPO2478 | SPO1150 | SPO2478 | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | RNA helicase; 'Novel gene detected by proteogenomics, SPO_PG024; identified in over 20 other Roseobacter strains'. | 0.572 |
| SPO1150 | SPO3833 | SPO1150 | SPO3833 | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | 0.572 |
| SPO1150 | nnrD | SPO1150 | SPO2293 | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.679 |
| SPO1150 | rhlE | SPO1150 | SPO1443 | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | ATP-dependent RNA helicase RhlE; Identified by similarity to SP:P25888; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | 0.572 |
| SPO1555 | SPO0833 | SPO1555 | SPO0833 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | 0.999 |
| SPO1555 | nnrD | SPO1555 | SPO2293 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.726 |
| SPO1555 | sdhB | SPO1555 | SPO0361 | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | Succinate dehydrogenase, iron-sulfur protein; Identified by match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.989 |
| SPO2478 | SPO1150 | SPO2478 | SPO1150 | RNA helicase; 'Novel gene detected by proteogenomics, SPO_PG024; identified in over 20 other Roseobacter strains'. | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.572 |
| SPO2478 | nnrD | SPO2478 | SPO2293 | RNA helicase; 'Novel gene detected by proteogenomics, SPO_PG024; identified in over 20 other Roseobacter strains'. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.762 |
| SPO3833 | SPO1150 | SPO3833 | SPO1150 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.572 |
| SPO3833 | nnrD | SPO3833 | SPO2293 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.762 |
| SPO3869 | nnrD | SPO3869 | SPO2293 | Putative protein TIGR00150; Identified by similarity to GB:AAK25496.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.759 |
| groEL | nnrD | SPO0887 | SPO2293 | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.864 |
| nadD | nnrD | SPO0449 | SPO2293 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.683 |
| nnrD | SPO0833 | SPO2293 | SPO0833 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | 0.726 |
| nnrD | SPO1150 | SPO2293 | SPO1150 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | RNA methyltransferase, TrmH family, group 3; Identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.679 |
| nnrD | SPO1555 | SPO2293 | SPO1555 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | Formate dehydrogenase, beta subunit; Identified by similarity to GB:AAN03798.1; match to protein family HMM PF01257; match to protein family HMM PF01512. | 0.726 |
