STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
glnB-1Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
amt-2
Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836.
 
 0.986
amt-1
Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836.
 
 0.984
glnD
protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.976
ntrB
Nitrogen regulation protein NtrB; Identified by similarity to SP:P09431; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 0.971
SPO1578
Identified by match to protein family HMM PF00909.
 
 0.907
glnB-2
Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family.
  
  
0.902
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P06201; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
 
 
 0.836
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.815
SPO1554
Identified by match to protein family HMM PF00909.
 
 
 0.787
nnrD
YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
       0.658
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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