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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dddPDMSP lyase; Identified by match to protein family HMM PF00557. (393 aa)    
Predicted Functional Partners:
dmdA
DmdA; Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating demethylation of dimethlysulfonioproprionate (DMSP) to methyl-mercaptopropionate (MMPA). The intracellular concentration of DMSP is estimated to be 70 mM. Belongs to the GcvT family. DmdA subfamily.
 
 
 0.738
SPO1441
Fatty acid desaturase family protein; Identified by match to protein family HMM PF00487.
  
  
  0.691
dddW
DMSP lyase; Able to cleave dimethlysulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS) and acrylate. DMS is the principal form by which sulfur is transported from oceans to the atmosphere.
  
  
 0.659
dddQ
DMSP lyase; May act as a dimethlysulfonioproprionate (DMSP) in vitro, releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere. The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo (Probable).
  
  
 0.659
dddD
DMSP lyase; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family.
      
 0.650
SPO2353
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.633
SPO1439
DNA binding protein, putative; Identified by match to protein family HMM PF01381.
 
     0.561
SPO1308
Hypothetical protein; Identified by similarity to PIR:F83007.
  
     0.511
dmdC
3-methylmercaptopropionyl-CoA dehydrogenase; Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating the conversion of 3-(methylthio)propanoyl- CoA (MMPA-CoA) to 3-(methylthio)acryloyl-CoA (MTA-CoA). Belongs to the acyl-CoA dehydrogenase family.
   
 
 0.464
dmdD
Methylthioacryloyl-CoA hydratase; Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by catalyzing both the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA.
    
 
 0.454
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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