| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO1058 | SPO2310 | SPO1058 | SPO2310 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | 0.918 |
| SPO1058 | SPO3444 | SPO1058 | SPO3444 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | 3-deoxy-D-manno-octulosonic-acid transferase, putative; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.951 |
| SPO1058 | kdsD | SPO1058 | SPO0082 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | Arabinose 5-phosphate isomerase; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.708 |
| SPO1058 | kdtA | SPO1058 | SPO2800 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.967 |
| SPO1058 | lpxA | SPO1058 | SPO1673 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.779 |
| SPO1058 | lpxB | SPO1058 | SPO1675 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.779 |
| SPO1058 | lpxC | SPO1058 | SPO1205 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.748 |
| SPO1058 | lpxD | SPO1058 | SPO1930 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.775 |
| SPO1058 | lpxK | SPO1058 | SPO3445 | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.808 |
| SPO2309 | SPO2310 | SPO2309 | SPO2310 | Membrane protein, putative; Identified by match to protein family HMM PF00892. | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | 0.778 |
| SPO2310 | SPO1058 | SPO2310 | SPO1058 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | Acyltransferase, HtrB family; Identified by similarity to GB:CAA74897.1; match to protein family HMM PF03279. | 0.918 |
| SPO2310 | SPO2309 | SPO2310 | SPO2309 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | Membrane protein, putative; Identified by match to protein family HMM PF00892. | 0.778 |
| SPO2310 | SPO3444 | SPO2310 | SPO3444 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | 3-deoxy-D-manno-octulosonic-acid transferase, putative; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.951 |
| SPO2310 | kdsD | SPO2310 | SPO0082 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | Arabinose 5-phosphate isomerase; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.767 |
| SPO2310 | kdtA | SPO2310 | SPO2800 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.970 |
| SPO2310 | lpxA | SPO2310 | SPO1673 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.789 |
| SPO2310 | lpxB | SPO2310 | SPO1675 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.801 |
| SPO2310 | lpxC | SPO2310 | SPO1205 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.775 |
| SPO2310 | lpxD | SPO2310 | SPO1930 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.788 |
| SPO2310 | lpxK | SPO2310 | SPO3445 | Lipid A biosynthesis lauroyl acyltransferase, putative; Identified by similarity to SP:P24187; match to protein family HMM PF03279. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.816 |