| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0635 | SPO1746 | SPO0635 | SPO1746 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | 0.626 |
| SPO0635 | SPO2344 | SPO0635 | SPO2344 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | 0.913 |
| SPO0635 | SPO2345 | SPO0635 | SPO2345 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | 0.870 |
| SPO0635 | SPO2346 | SPO0635 | SPO2346 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Sarcosine oxidase, delta subunit family; Identified by similarity to SP:Q46336; match to protein family HMM PF04267. | 0.947 |
| SPO0635 | SPO2348 | SPO0635 | SPO2348 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Sarcosine oxidase, beta subunit family; Identified by similarity to SP:P40875; match to protein family HMM PF01266; match to protein family HMM TIGR01373. | 0.744 |
| SPO0635 | SPO3327 | SPO0635 | SPO3327 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Creatinase; Identified by similarity to SP:P38488; match to protein family HMM PF00557; match to protein family HMM PF01321. | 0.915 |
| SPO0635 | glyA-1 | SPO0635 | SPO1572 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.937 |
| SPO0635 | glyA-3 | SPO0635 | SPO3529 | Aminomethyl transferase family protein; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Identified by match to protein family HMM PF00464. | 0.937 |
| SPO1746 | SPO0635 | SPO1746 | SPO0635 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | Aminomethyl transferase family protein; Belongs to the GcvT family. | 0.626 |
| SPO1746 | SPO2344 | SPO1746 | SPO2344 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | 0.909 |
| SPO1746 | SPO2346 | SPO1746 | SPO2346 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | Sarcosine oxidase, delta subunit family; Identified by similarity to SP:Q46336; match to protein family HMM PF04267. | 0.960 |
| SPO1746 | SPO2348 | SPO1746 | SPO2348 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | Sarcosine oxidase, beta subunit family; Identified by similarity to SP:P40875; match to protein family HMM PF01266; match to protein family HMM TIGR01373. | 0.895 |
| SPO1746 | glyA-1 | SPO1746 | SPO1572 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.468 |
| SPO1746 | glyA-3 | SPO1746 | SPO3529 | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Identified by match to protein family HMM PF00464. | 0.468 |
| SPO2344 | SPO0635 | SPO2344 | SPO0635 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | Aminomethyl transferase family protein; Belongs to the GcvT family. | 0.913 |
| SPO2344 | SPO1746 | SPO2344 | SPO1746 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | 0.909 |
| SPO2344 | SPO2345 | SPO2344 | SPO2345 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | Sarcosine oxidase, alpha subunit family; Identified by similarity to SP:Q46337; match to protein family HMM PF01571; match to protein family HMM TIGR01372; Belongs to the GcvT family. | 0.998 |
| SPO2344 | SPO2346 | SPO2344 | SPO2346 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | Sarcosine oxidase, delta subunit family; Identified by similarity to SP:Q46336; match to protein family HMM PF04267. | 0.999 |
| SPO2344 | SPO2348 | SPO2344 | SPO2348 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | Sarcosine oxidase, beta subunit family; Identified by similarity to SP:P40875; match to protein family HMM PF01266; match to protein family HMM TIGR01373. | 0.979 |
| SPO2344 | SPO3156 | SPO2344 | SPO3156 | Sarcosine oxidase, gamma subunit family; Identified by similarity to SP:Q46338; match to protein family HMM PF04268. | L-threonine aldolase, low-specificity, putative; Identified by similarity to SP:O50584. | 0.920 |