SPO2530 protein (Ruegeria pomeroyi) - STRING interaction network

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

SPO2530

Branched-chain amino acid ABC transporter, permease protein; Identified by similarity to SP:P22729; match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family. (340 aa)

Predicted Functional Partners:

SPO2531

0.997

SPO2533

0.986

SPO2532

0.981

SPO0823

0.969

SPO1849

0.962

SPO2534

0.960

SPO1018

0.955

livF-1

0.954

SPO1829

0.952

SPO1848

0.952

Your Current Organism:

Ruegeria pomeroyi

NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPO0823	SPO1848	SPO0823	SPO1848	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Assignment partly based on membership in branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF00005.	0.516
SPO0823	SPO2530	SPO0823	SPO2530	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, permease protein; Identified by similarity to SP:P22729; match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.	0.969
SPO0823	SPO2531	SPO0823	SPO2531	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, permease protein; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.	0.825
SPO0823	SPO2532	SPO0823	SPO2532	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22731; match to protein family HMM PF00005.	0.527
SPO0823	SPO2534	SPO0823	SPO2534	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Assignment partly based on membership in an branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF01094; match to protein family HMM TIGR01409.	0.479
SPO0823	livF-1	SPO0823	SPO1831	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22731; match to protein family HMM PF00005.	0.517
SPO1018	SPO1848	SPO1018	SPO1848	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Assignment partly based on membership in branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF00005.	0.482
SPO1018	SPO2530	SPO1018	SPO2530	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, permease protein; Identified by similarity to SP:P22729; match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.	0.955
SPO1018	SPO2531	SPO1018	SPO2531	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, permease protein; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.	0.800
SPO1018	SPO2532	SPO1018	SPO2532	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22731; match to protein family HMM PF00005.	0.517
SPO1018	livF-1	SPO1018	SPO1831	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22731; match to protein family HMM PF00005.	0.934
SPO1829	SPO1848	SPO1829	SPO1848	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	Assignment partly based on membership in branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF00005.	0.482
SPO1829	SPO2530	SPO1829	SPO2530	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, permease protein; Identified by similarity to SP:P22729; match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.	0.952
SPO1829	SPO2531	SPO1829	SPO2531	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, permease protein; Identified by match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.	0.854
SPO1829	SPO2532	SPO1829	SPO2532	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22731; match to protein family HMM PF00005.	0.503
SPO1829	SPO2534	SPO1829	SPO2534	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	Assignment partly based on membership in an branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF01094; match to protein family HMM TIGR01409.	0.471
SPO1829	livF-1	SPO1829	SPO1831	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22731; match to protein family HMM PF00005.	0.748
SPO1848	SPO0823	SPO1848	SPO0823	Assignment partly based on membership in branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	0.516
SPO1848	SPO1018	SPO1848	SPO1018	Assignment partly based on membership in branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P22730; match to protein family HMM PF00005.	0.482
SPO1848	SPO1829	SPO1848	SPO1829	Assignment partly based on membership in branched-chain amino acid ABC transporter gene cluster; identified by match to protein family HMM PF00005.	Branched-chain amino acid ABC transporter, ATP-binding protein; Identified by similarity to SP:P21629; match to protein family HMM PF00005.	0.482

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Network Stats

number of nodes:

4

number of edges:

3

average node degree:

1.5

avg. local clustering coefficient:

0.75

expected number of edges:

4

PPI enrichment p-value:

0.687

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042777

Proton motive force-driven plasma membrane ATP synthesis

4 of 5

2.25

2.9

1.83e-06

GO:0015986

Proton motive force-driven ATP synthesis

5 of 13

1.94

2.81

6.06e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015078

Proton transmembrane transporter activity

9 of 19

2.03

5.37

2.10e-14

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

7 of 9

2.24

5.17

5.89e-12

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

6 of 14

1.98

3.71

2.44e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016469

Proton-transporting two-sector ATPase complex

9 of 17

2.07

5.87

1.54e-15

GO:0033176

Proton-transporting V-type ATPase complex

5 of 5

2.35

4.16

4.28e-09

GO:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

4 of 7

2.11

2.87

1.18e-06

GO:0033179

Proton-transporting V-type ATPase, V0 domain

3 of 3

2.35

2.47

1.86e-05

GO:0045259

Proton-transporting ATP synthase complex

3 of 11

1.79

1.67

0.00028

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1566

ATPase-coupled ion transmembrane transporter activity, and ATP synthase subunit C

11 of 11

2.35

9.0

7.69e-22

CL:1570

ATPase-coupled ion transmembrane transporter activity

6 of 6

2.35

4.85

1.09e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

9 of 36

1.75

3.99

4.95e-13

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

8 of 23

1.89

4.51

5.86e-13

MAP-168256

Immune System

8 of 26

1.84

4.3

6.73e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016469

Proton-transporting two-sector ATPase complex

8 of 20

1.95

4.53

2.81e-12

GOCC:0033176

Proton-transporting V-type ATPase complex

5 of 8

2.15

3.48

4.90e-08

GOCC:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

3 of 10

1.83

1.56

0.00059

GOCC:0033179

Proton-transporting V-type ATPase, V0 domain

2 of 5

1.95

1.03

0.0103

GOCC:0005773

Vacuole

2 of 5

1.95

1.03

0.0103

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0406

Ion transport

4 of 18

1.7

1.62

0.00026

KW-0375

Hydrogen ion transport

3 of 11

1.79

1.32

0.0020

KW-0066

ATP synthesis

3 of 11

1.79

1.32

0.0020

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