| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO2680 | SPO3176 | SPO2680 | SPO3176 | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | Prephenate dehydrogenase; Identified by similarity to SP:Q04983; match to protein family HMM PF02153. | 0.577 |
| SPO2680 | ilvC | SPO2680 | SPO1366 | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.552 |
| SPO2680 | petP | SPO2680 | SPO0252 | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | Transcriptional regulator PetP; Identified by similarity to SP:P31078; match to protein family HMM PF01047. | 0.453 |
| SPO2680 | tatA | SPO2680 | SPO2683 | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.707 |
| SPO2680 | tatB | SPO2680 | SPO2682 | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.707 |
| SPO2680 | tatC | SPO2680 | SPO2681 | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.707 |
| SPO3176 | SPO2680 | SPO3176 | SPO2680 | Prephenate dehydrogenase; Identified by similarity to SP:Q04983; match to protein family HMM PF02153. | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | 0.577 |
| ilvC | SPO2680 | SPO1366 | SPO2680 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | 0.552 |
| petP | SPO2680 | SPO0252 | SPO2680 | Transcriptional regulator PetP; Identified by similarity to SP:P31078; match to protein family HMM PF01047. | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | 0.453 |
| tatA | SPO2680 | SPO2683 | SPO2680 | Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | 0.707 |
| tatA | tatB | SPO2683 | SPO2682 | Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.999 |
| tatA | tatC | SPO2683 | SPO2681 | Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.997 |
| tatB | SPO2680 | SPO2682 | SPO2680 | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | 0.707 |
| tatB | tatA | SPO2682 | SPO2683 | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.999 |
| tatB | tatC | SPO2682 | SPO2681 | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.998 |
| tatC | SPO2680 | SPO2681 | SPO2680 | Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | Hypothetical protein; Identified by similarity to GB:BAB48529.1; match to protein family HMM PF05673. | 0.707 |
| tatC | tatA | SPO2681 | SPO2683 | Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.997 |
| tatC | tatB | SPO2681 | SPO2682 | Twin-arginine translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.998 |