Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdMType I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497. (900 aa)    
Predicted Functional Partners:
hsdS
Type I restriction-modification system, S subunit; Identified by similarity to SP:P05719; match to protein family HMM PF01420.
 
 
 0.999
hsdR
Type I restriction-modification system, R subunit; Identified by match to protein family HMM PF04313; match to protein family HMM TIGR00348.
 
  
 0.995
SPO3899
Hypothetical protein; Identified by similarity to GB:BAD02160.1; match to protein family HMM PF01863.
 
     0.949
SPO2736
Hypothetical protein; Identified by similarity to GB:CAD79234.1.
 
     0.886
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.519
SPO1926
Hypothetical protein; Identified by similarity to GB:AAK22811.1.
  
  
 0.504
SPO3622
Hypothetical protein; Identified by similarity to GB:BAC46174.1; match to protein family HMM PF01863.
 
     0.495
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
   
 
 0.473
SPO2981
Hypothetical protein; Identified by similarity to GB:CAC67530.1.
  
  
 0.404
SPO0960
Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376.
 
   0.402
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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