Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPO2748Hypothetical protein; Identified by similarity to PIR:AG2090. (195 aa)    
Predicted Functional Partners:
SPO3409
Anti-anti-sigma factor; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
 
    0.990
SPO3410
Anti-sigma B factor, putative; Identified by similarity to SP:P17904; match to protein family HMM PF02518.
  
    0.988
SPO2747
Diguanylate cyclase, putative; Identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
  
 0.978
flgB
Flagellar basal-body rod protein; Identified by similarity to SP:P24500; similarity to SP:P75934.
   
    0.971
SPO0022
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF07228.
  
    0.955
SPO0021
Hpt domain protein; Identified by match to protein family HMM PF01627.
 
    0.883
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.880
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
  
 0.830
SPO1742
Hypothetical protein; Identified by similarity to GB:BAB54226.1.
   
    0.826
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
  
  
 0.803
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.