Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPO2862CobW; Identified by similarity to SP:P29937; match to protein family HMM PF02492; match to protein family HMM PF07683. (351 aa)    
Predicted Functional Partners:
SPO2863
CobN; Identified by similarity to SP:P29929; match to protein family HMM PF02514.
 
  
 0.968
SPO2861
Hypothetical protein; Identified by similarity to PIR:AE2921.
 
    0.927
SPO2864
CobG; Identified by similarity to SP:P21637; match to protein family HMM PF03460; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
   
 0.926
cobI
Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
 
   
 0.926
cobH
precorrin-8X methylmutase; Identified by similarity to SP:P21638; match to protein family HMM PF02570.
 
   
 0.906
cobJ
precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466.
 
   
 0.882
cobL
precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01468.
 
   
 0.819
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.723
rpsN
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.696
folE2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.657
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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