Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobJprecorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466. (250 aa)    
Predicted Functional Partners:
cobH
precorrin-8X methylmutase; Identified by similarity to SP:P21638; match to protein family HMM PF02570.
  
 0.999
cobI
Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
 
 0.999
cobM
Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family.
 
 0.999
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.995
SPO2864
CobG; Identified by similarity to SP:P21637; match to protein family HMM PF03460; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.995
cobK
Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715.
  
 0.989
cobL
precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01468.
 
  
 0.984
SPO2863
CobN; Identified by similarity to SP:P29929; match to protein family HMM PF02514.
 
  
 0.970
cobF
precorrin-6A synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.
 
  
 0.968
SPO2870
Cobalamin biosynthesis domain protein.
 
  
 0.950
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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