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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO2956Guanine deaminase, putative; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (427 aa)    
Predicted Functional Partners:
xdhB
Xanthine dehydrogenase, B subunit; Identified by similarity to GB:CAA04470.2.
 
 
 0.975
xdhA
Xanthine dehydrogenase, A subunit; Identified by similarity to GB:CAA04469.1.
 
  
  0.970
hpt
Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P37171; match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.911
iunH
Inosine-uridine preferring nucleoside hydrolase; Identified by match to protein family HMM PF01156.
  
 
 0.910
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.909
deoD
Purine nucleoside phosphorylase; Identified by similarity to SP:O34925; match to protein family HMM PF01048; match to protein family HMM TIGR00107.
     
 0.900
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
 0.900
xdhC
Xanthine dehydrogenase accessory factor; Identified by similarity to GB:CAB41849.1.
 
 
  0.858
SPO0872
Polysaccharide deacetylase family protein.
 
   
 0.796
SPO0871
Identified by match to protein family HMM PF00576; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.773
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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