| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ccoN-1 | ctaC | SPO3526 | SPO3076 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | 0.981 |
| ccoN-1 | ctaD | SPO3526 | SPO1383 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | Cytochrome c oxidase, aa3-type, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | 0.975 |
| ccoN-1 | ctaE | SPO3526 | SPO3073 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | Cytochrome c oxidase, subunit III; Identified by match to protein family HMM PF00510. | 0.976 |
| ccoN-1 | cyoE | SPO3526 | SPO3075 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.920 |
| ccoN-1 | nuoA | SPO3526 | SPO2786 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | NADH dehydrogenase I, A subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. | 0.786 |
| ccoN-1 | nuoH | SPO3526 | SPO2772 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | NADH dehydrogenase I, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. | 0.763 |
| ccoN-1 | nuoM | SPO3526 | SPO2764 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | NADH dehydrogenase I, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972. | 0.865 |
| ccoN-1 | nuoN | SPO3526 | SPO2763 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | NADH dehydrogenase I, N subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.715 |
| ccoN-1 | petB | SPO3526 | SPO0272 | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.924 |
| ctaC | ccoN-1 | SPO3076 | SPO3526 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | 0.981 |
| ctaC | ctaD | SPO3076 | SPO1383 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Cytochrome c oxidase, aa3-type, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | 0.999 |
| ctaC | ctaE | SPO3076 | SPO3073 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Cytochrome c oxidase, subunit III; Identified by match to protein family HMM PF00510. | 0.999 |
| ctaC | ctaG | SPO3076 | SPO3074 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Cytochrome c oxidase assembly protein CtaG; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. | 0.982 |
| ctaC | cyoE | SPO3076 | SPO3075 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.999 |
| ctaC | nuoA | SPO3076 | SPO2786 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | NADH dehydrogenase I, A subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. | 0.982 |
| ctaC | nuoH | SPO3076 | SPO2772 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | NADH dehydrogenase I, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. | 0.985 |
| ctaC | nuoM | SPO3076 | SPO2764 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | NADH dehydrogenase I, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972. | 0.979 |
| ctaC | nuoN | SPO3076 | SPO2763 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | NADH dehydrogenase I, N subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.984 |
| ctaC | petB | SPO3076 | SPO0272 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.997 |
| ctaD | ccoN-1 | SPO1383 | SPO3526 | Cytochrome c oxidase, aa3-type, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | Cytochrome c oxidase, cbb3-type, subunit I; Identified by similarity to SP:P98059; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family. | 0.975 |
