STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO3341Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. (306 aa)    
Predicted Functional Partners:
ilvN
Acetolactate synthase, small subunit; Identified by similarity to SP:P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119.
  
 
 0.950
thrC
Threonine synthase; Identified by similarity to GB:CAA82670.1; match to protein family HMM PF00291; match to protein family HMM TIGR00260.
  
 
 0.945
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
 
 
 0.934
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.927
SPO1142
Threonine dehydratase, putative; Identified by match to protein family HMM PF00291.
  
  
 
0.924
SPO2385
Benzaldehyde lyase, putative; Identified by similarity to SP:P51853; match to protein family HMM PF00205; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
  
 0.924
ilvB
Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to GB:AAL99356.1; match to protein family HMM PF00205; match to protein family HMM PF02776; match to protein family HMM TIGR00118.
  
 0.924
SPO2883
Thiamine pyrophosphate-binding domain protein; Identified by match to protein family HMM PF02776.
  
 0.924
SPO2885
Acetolactate synthase, catabolic, putative; Identified by similarity to SP:P27696; match to protein family HMM PF00205; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
  
 0.924
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
  
 
0.923
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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