STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO3354Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (393 aa)    
Predicted Functional Partners:
serA
D-3-phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 0.998
serB-2
Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.
  
 
 0.975
serB-1
Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488.
  
 
 0.962
thrC
Threonine synthase; Identified by similarity to GB:CAA82670.1; match to protein family HMM PF00291; match to protein family HMM TIGR00260.
  
 0.957
SPO1921
Pyridoxal-phosphate dependent enzyme; Identified by match to protein family HMM PF00291.
  
 
 0.920
cysK
Cysteine synthase A; Identified by similarity to SP:P37887; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.
  
 
 0.920
pdxA-1
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
     
 0.918
SPO1700
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF02826.
 
 
 0.831
SPO0415
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF02826.
  
 
 0.822
SPO3539
Prephenate dehydratase; Identified by similarity to PIR:AC3490; match to protein family HMM PF00800.
  
  
 0.732
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (24%) [HD]