Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPO3443Identified by similarity to SP:P22783; match to protein family HMM PF00459. (267 aa)    
Predicted Functional Partners:
SPO3012
Inositol-1-monophosphatase, putative; Identified by similarity to SP:P22783; match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily.
  
  
 
0.924
SPO3442
PmbA; Identified by similarity to SP:P24231.
       0.836
SPO3441
Hypothetical protein; Identified by similarity to GB:AAC02256.1.
       0.707
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
       0.632
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.609
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
   0.592
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
   
   0.578
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
   
 
 0.575
SPO3444
3-deoxy-D-manno-octulosonic-acid transferase, putative; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
       0.535
SPO3439
Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.524
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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