| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0006 | mutY | SPO0006 | SPO3448 | Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.646 |
| SPO3425 | dnaN | SPO3425 | SPO0150 | Exodeoxyribonuclease III, putative; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.802 |
| SPO3425 | mutM | SPO3425 | SPO0146 | Exodeoxyribonuclease III, putative; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.443 |
| SPO3425 | mutY | SPO3425 | SPO3448 | Exodeoxyribonuclease III, putative; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.797 |
| SPO3425 | xth | SPO3425 | SPO2509 | Exodeoxyribonuclease III, putative; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.924 |
| SPO3446 | SPO3447 | SPO3446 | SPO3447 | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | Hypothetical protein; Identified by similarity to GB:CAE29927.1. | 0.850 |
| SPO3446 | SPO3449 | SPO3446 | SPO3449 | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | Fatty acid desaturase family protein; Identified by match to protein family HMM PF00487. | 0.466 |
| SPO3446 | dnaN | SPO3446 | SPO0150 | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.419 |
| SPO3446 | mutY | SPO3446 | SPO3448 | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.702 |
| SPO3447 | SPO3446 | SPO3447 | SPO3446 | Hypothetical protein; Identified by similarity to GB:CAE29927.1. | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | 0.850 |
| SPO3447 | SPO3449 | SPO3447 | SPO3449 | Hypothetical protein; Identified by similarity to GB:CAE29927.1. | Fatty acid desaturase family protein; Identified by match to protein family HMM PF00487. | 0.479 |
| SPO3447 | mutY | SPO3447 | SPO3448 | Hypothetical protein; Identified by similarity to GB:CAE29927.1. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.690 |
| SPO3449 | SPO3446 | SPO3449 | SPO3446 | Fatty acid desaturase family protein; Identified by match to protein family HMM PF00487. | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | 0.466 |
| SPO3449 | SPO3447 | SPO3449 | SPO3447 | Fatty acid desaturase family protein; Identified by match to protein family HMM PF00487. | Hypothetical protein; Identified by similarity to GB:CAE29927.1. | 0.479 |
| SPO3449 | mutY | SPO3449 | SPO3448 | Fatty acid desaturase family protein; Identified by match to protein family HMM PF00487. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.651 |
| dnaN | SPO3425 | SPO0150 | SPO3425 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III, putative; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | 0.802 |
| dnaN | SPO3446 | SPO0150 | SPO3446 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thiol:disulfide interchange protein, DsbA family; Identified by match to protein family HMM PF01323. | 0.419 |
| dnaN | mutL | SPO0150 | SPO3362 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.935 |
| dnaN | mutM | SPO0150 | SPO0146 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.515 |
| dnaN | mutY | SPO0150 | SPO3448 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.815 |
