STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO3575Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376. (118 aa)    
Predicted Functional Partners:
SPO3574
Hypothetical protein; Identified by similarity to GB:CAD17119.1.
       0.773
SPO0960
Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376.
 
 
 
 0.709
SPO3573
NADPH-dependent FMN reductase domain protein; Identified by match to protein family HMM PF03358.
  
  
 0.528
SPO3734
Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376.
 
 
 
 0.518
SPO3576
OmpA domain protein; Identified by match to protein family HMM PF00691.
  
    0.481
soxR
Redox-sensitive transcriptional activator SoxR; Identified by match to protein family HMM PF00376; match to protein family HMM TIGR01950.
  
   
 0.480
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.444
SPO2850
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
 
 0.444
SPO0794
Copper-translocating P-type ATPase; Identified by similarity to SP:P37279; match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
  
  
 0.436
SPO0132
Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
   
 
 0.427
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.