Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPO36547-alpha-hydroxysteroid dehydrogenase, putative; Identified by similarity to SP:P25529; match to protein family HMM PF00106. (266 aa)    
Predicted Functional Partners:
hemF
Coproporphyrinogen III oxidase, aerobic; Identified by match to protein family HMM PF01218.
     
 0.768
phbB
acetoacetyl-CoA reductase; Identified by similarity to SP:P23238; match to protein family HMM PF00106; match to protein family HMM TIGR01829.
  
     0.767
SPO1957
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by similarity to GB:AAR05249.1; match to protein family HMM PF00106.
  
 
 
 0.714
SPO1480
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106.
  
 
 0.677
SPO2679
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106.
 
    0.677
SPO1965
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.660
SPO3655
Methyltransferase, putative; Identified by match to protein family HMM PF05175; Belongs to the methyltransferase superfamily.
       0.655
SPO0724
Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
 0.564
clpS
ATP-dependent Clp protease, adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.539
SPO2842
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106.
 
    
0.516
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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