Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tyrBAromatic amino acid aminotransferase; Identified by similarity to SP:P95468; match to protein family HMM PF00155. (394 aa)    
Predicted Functional Partners:
SPO3719
Thiosulfate sulfurtransferase, putative; Identified by similarity to PIR:T52663; match to protein family HMM PF00581.
 
 
 0.986
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.962
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM TIGR01263.
  
 
 0.950
SPO1743
Glutamate dehydrogenase; Identified by similarity to SP:P96110; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.943
SPO3539
Prephenate dehydratase; Identified by similarity to PIR:AC3490; match to protein family HMM PF00800.
    
 0.943
SPO3717
Identified by match to protein family HMM PF00883; Belongs to the peptidase M17 family.
  
 0.932
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.924
argG
Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.923
cysK
Cysteine synthase A; Identified by similarity to SP:P37887; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.
   
 0.921
gltD
Glutamate synthase, small subunit; Identified by similarity to GB:AAG38999.1; match to protein family HMM PF00070; match to protein family HMM TIGR01318.
 
  
 0.920
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (18%) [HD]