| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO1280 | SPO1394 | SPO1280 | SPO1394 | Hypothetical protein; Identified by similarity to SP:Q92W37; match to protein family HMM PF05114; Belongs to the UPF0276 family. | Beta-lactamase, putative; Identified by match to protein family HMM PF00144; match to protein family HMM PF00353. | 0.804 |
| SPO1280 | SPO3789 | SPO1280 | SPO3789 | Hypothetical protein; Identified by similarity to SP:Q92W37; match to protein family HMM PF05114; Belongs to the UPF0276 family. | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.450 |
| SPO1394 | SPO1280 | SPO1394 | SPO1280 | Beta-lactamase, putative; Identified by match to protein family HMM PF00144; match to protein family HMM PF00353. | Hypothetical protein; Identified by similarity to SP:Q92W37; match to protein family HMM PF05114; Belongs to the UPF0276 family. | 0.804 |
| SPO1394 | SPO3789 | SPO1394 | SPO3789 | Beta-lactamase, putative; Identified by match to protein family HMM PF00144; match to protein family HMM PF00353. | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.407 |
| SPO3383 | SPO3789 | SPO3383 | SPO3789 | Thiol-specific antioxidant protein; Identified by similarity to GB:BAC00970.1; match to protein family HMM PF00578. | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.422 |
| SPO3789 | SPO1280 | SPO3789 | SPO1280 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Hypothetical protein; Identified by similarity to SP:Q92W37; match to protein family HMM PF05114; Belongs to the UPF0276 family. | 0.450 |
| SPO3789 | SPO1394 | SPO3789 | SPO1394 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Beta-lactamase, putative; Identified by match to protein family HMM PF00144; match to protein family HMM PF00353. | 0.407 |
| SPO3789 | SPO3383 | SPO3789 | SPO3383 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Thiol-specific antioxidant protein; Identified by similarity to GB:BAC00970.1; match to protein family HMM PF00578. | 0.422 |
| SPO3789 | acoA | SPO3789 | SPO3792 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | 0.534 |
| SPO3789 | acoB | SPO3789 | SPO3791 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Acetoin dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780. | 0.606 |
| SPO3789 | acoC | SPO3789 | SPO3790 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561. | 0.717 |
| SPO3789 | acoR | SPO3789 | SPO3788 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Acetoin catabolism regulatory protein; Identified by similarity to SP:P28614; match to protein family HMM PF00158; match to protein family HMM PF01590. | 0.473 |
| SPO3789 | acoX | SPO3789 | SPO3793 | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Acetoin catabolism protein X; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.666 |
| acoA | SPO3789 | SPO3792 | SPO3789 | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.534 |
| acoA | acoB | SPO3792 | SPO3791 | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | Acetoin dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780. | 0.999 |
| acoA | acoC | SPO3792 | SPO3790 | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | Acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561. | 0.907 |
| acoA | acoR | SPO3792 | SPO3788 | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | Acetoin catabolism regulatory protein; Identified by similarity to SP:P28614; match to protein family HMM PF00158; match to protein family HMM PF01590. | 0.472 |
| acoA | acoX | SPO3792 | SPO3793 | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | Acetoin catabolism protein X; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.950 |
| acoB | SPO3789 | SPO3791 | SPO3789 | Acetoin dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780. | 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.606 |
| acoB | acoA | SPO3791 | SPO3792 | Acetoin dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780. | Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676. | 0.999 |