Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
acoXAcetoin catabolism protein X; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (352 aa)    
Predicted Functional Partners:
acoA
Acetoin dehydrogenase complex, E1 component, alpha subunit; Identified by similarity to PIR:I40790; match to protein family HMM PF00676.
 
  
 0.950
acoB
Acetoin dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780.
 
  
 0.930
acoC
Acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561.
 
  
 0.929
acoR
Acetoin catabolism regulatory protein; Identified by similarity to SP:P28614; match to protein family HMM PF00158; match to protein family HMM PF01590.
 
   
 0.795
SPO3789
4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.665
SPO3787
Assignment partly based on membership in sugar ABC transporter gene cluster; identified by match to protein family HMM TIGR01409.
 
     0.647
SPO0585
Dehydrogenase/transketolase family protein.
 
  
 0.600
pdhB
Pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
  
 0.599
SPO3794
Hypothetical protein; Identified by similarity to GB:AAM35022.1.
 
     0.572
SPO3781
Hypothetical protein; Identified by similarity to PIR:AB1999; match to protein family HMM TIGR02058.
 
     0.532
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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