STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO3812Identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; Belongs to the peptidase S41A family. (443 aa)    
Predicted Functional Partners:
SPO3811
Hypothetical protein; Identified by similarity to GB:AAK25396.1.
  
  
 0.927
SPO2903
TPR/sulfotransferase domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF00685.
  
 
 0.846
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.846
rppH
Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
   
 0.806
SPO3008
TPR domain protein; Identified by match to protein family HMM PF00515.
    
 
 0.745
SPO3718
Identified by match to protein family HMM PF00877.
    
 
 0.632
mltG
Putative protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
   
 0.578
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
    0.547
SPO1668
Membrane-associated zinc metalloprotease, putative; Identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054.
 
  
 0.515
mrca
Penicillin-binding protein 1A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
 
     0.513
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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