| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO3833 | hrpB | SPO3833 | SPO0972 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | 0.727 |
| SPO3833 | nnrD | SPO3833 | SPO2293 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.762 |
| SPO3833 | pnp | SPO3833 | SPO3389 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.800 |
| SPO3833 | recQ | SPO3833 | SPO0107 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.934 |
| SPO3833 | rplC | SPO3833 | SPO3825 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.788 |
| SPO3833 | rplD | SPO3833 | SPO3824 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.762 |
| SPO3833 | rplM | SPO3833 | SPO1691 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.694 |
| SPO3833 | rplW | SPO3833 | SPO3823 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.685 |
| SPO3833 | rpoC | SPO3833 | SPO3507 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.722 |
| SPO3833 | rrmJ | SPO3833 | SPO1858 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.739 |
| hrpB | SPO3833 | SPO0972 | SPO3833 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | 0.727 |
| hrpB | recQ | SPO0972 | SPO0107 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.405 |
| hrpB | rplC | SPO0972 | SPO3825 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.753 |
| hrpB | rplD | SPO0972 | SPO3824 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.757 |
| hrpB | rplM | SPO0972 | SPO1691 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.691 |
| hrpB | rplW | SPO0972 | SPO3823 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.696 |
| hrpB | rpoC | SPO0972 | SPO3507 | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.825 |
| nnrD | SPO3833 | SPO2293 | SPO3833 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. | 0.762 |
| nnrD | pnp | SPO2293 | SPO3389 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.469 |
| nnrD | rplM | SPO2293 | SPO1691 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.432 |
