| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO2469 | maf-1 | SPO2469 | SPO3892 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.907 |
| SPO2469 | ndk | SPO2469 | SPO2444 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| SPO2469 | pyrG | SPO2469 | SPO1312 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.911 |
| SPO2469 | pyrH | SPO2469 | SPO1662 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| SPO2469 | surE | SPO2469 | SPO2688 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.908 |
| SPO2469 | tdk | SPO2469 | SPO0914 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Thymidine kinase; Identified by similarity to SP:P23331; match to protein family HMM PF00265. | 0.900 |
| SPO2469 | thyX | SPO2469 | SPO1273 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.942 |
| SPO2469 | tmk | SPO2469 | SPO2740 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.921 |
| SPO2469 | upp | SPO2469 | SPO2926 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.909 |
| aroE | maf-1 | SPO3891 | SPO3892 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.916 |
| maf-1 | SPO2469 | SPO3892 | SPO2469 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.907 |
| maf-1 | aroE | SPO3892 | SPO3891 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.916 |
| maf-1 | ndk | SPO3892 | SPO2444 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.911 |
| maf-1 | pyrG | SPO3892 | SPO1312 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.909 |
| maf-1 | pyrH | SPO3892 | SPO1662 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| maf-1 | surE | SPO3892 | SPO2688 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| maf-1 | tdk | SPO3892 | SPO0914 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidine kinase; Identified by similarity to SP:P23331; match to protein family HMM PF00265. | 0.900 |
| maf-1 | thyX | SPO3892 | SPO1273 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
| maf-1 | tmk | SPO3892 | SPO2740 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.913 |
| maf-1 | upp | SPO3892 | SPO2926 | Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.901 |
