STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smfDNA processing chain A. (354 aa)    
Predicted Functional Partners:
comF
Putative competence protein F.
 
 
 0.847
comM
Mg chelatase-related protein.
 
 0.807
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.665
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.651
ssb
Single-stranded DNA-binding protein ssb; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 0.585
fdxA
Ferredoxin 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
       0.558
BAO99424.1
Hypothetical protein.
       0.528
radC
DNA repair protein RadC.
  
  
 0.504
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.431
ftsQ
Cell division protein FtsQ putative.
       0.419
Your Current Organism:
Wolbachia endosymbiont of Cimex
NCBI taxonomy Id: 246273
Other names: W. endosymbiont of Cimex lectularius, Wolbachia endosymbiont of Cimex lectularius
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.