STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase complex E1 component pyruvate dehydrogenase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (327 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase complex E1 component pyruvate dehydrogenase beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
pdhC
Pyruvate dehydrogenase complex E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
lpd-2
Dihydrolipoamide dehydrogenase.
  
 
 0.997
lpd
Alpha keto acid dehydrogenase complex E3 component lipoamide dehydrogenase.
  
 
 0.994
maeB
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.974
sucB
2-oxoglutarate dehydrogenase E2 component dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
 0.974
ppdK
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.918
sucA
2-oxoglutarate dehydrogenase E1 component.
     
 0.903
tkt
Transketolase; Belongs to the transketolase family.
  
 
 0.875
prsA
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
    
 0.833
Your Current Organism:
Wolbachia endosymbiont of Cimex
NCBI taxonomy Id: 246273
Other names: W. endosymbiont of Cimex lectularius, Wolbachia endosymbiont of Cimex lectularius
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