Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhAPyruvate dehydrogenase complex E1 component pyruvate dehydrogenase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (327 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase complex E1 component pyruvate dehydrogenase beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
pdhC
Pyruvate dehydrogenase complex E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.998
lpd-2
Dihydrolipoamide dehydrogenase.
  
 
 0.991
lpd
Alpha keto acid dehydrogenase complex E3 component lipoamide dehydrogenase.
  
 
 0.985
maeB
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.969
sucB
2-oxoglutarate dehydrogenase E2 component dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
 0.949
ppdK
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.919
tkt
Transketolase; Belongs to the transketolase family.
  
 
 0.872
BAO99333.1
Membrane associated signal transduction histidine kinase and receiver domain.
    
 0.850
sucA
2-oxoglutarate dehydrogenase E1 component.
     
 0.828
Your Current Organism:
Wolbachia endosymbiont of Cimex
NCBI taxonomy Id: 246273
Other names: W. endosymbiont of Cimex lectularius, Wolbachia endosymbiont of Cimex lectularius
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