STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RO3G_141843-hydroxy-3-methylglutaryl coenzyme A reductase. (1025 aa)    
Predicted Functional Partners:
RO3G_13071
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.986
RO3G_06702
Uncharacterized protein.
   
 
 0.912
RO3G_00394
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 0.890
RO3G_11218
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
 
 0.873
RO3G_04399
Uncharacterized protein.
   
 
 0.807
RO3G_14809
Uncharacterized protein.
   
 
 0.807
RO3G_02884
Uncharacterized protein.
    
 0.803
RO3G_00920
SE domain-containing protein.
   
  
 0.767
RO3G_02215
Uncharacterized protein.
   
  
 0.767
RO3G_11081
SE domain-containing protein.
   
  
 0.767
Your Current Organism:
Rhizopus delemar
NCBI taxonomy Id: 246409
Other names: R. delemar RA 99-880, Rhizopus delemar RA 99-880, Rhizopus delemar RA99-880
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