STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIMG_00136CMGC/DYRK/DYRK2 protein kinase. (1431 aa)    
Predicted Functional Partners:
CIMG_08858
WD repeat protein.
   
 
 0.861
CIMG_06854
Rho GTPase activator Rga.
    
 
 0.807
CIMG08773
PLK protein kinase.
    
 
0.791
CIMG_09391
Septum-promoting GTP-binding protein 1.
    
 
 0.774
CIMG_04103
STE/STE11/CDC15 protein kinase.
    
  
0.774
CIMG_10025
AGC/NDR/NDR-UNCLASSIFIED protein kinase.
    
 
0.667
CIMG_11861
Ubiquitin-like modifier SUMO.
    
 0.633
CIMG09299
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.632
CIMG_04120
SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.627
CIMG05383
AGC/PKA protein kinase; Belongs to the protein kinase superfamily.
   
 
0.503
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.