STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PXR1Protein PXR1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family. (317 aa)    
Predicted Functional Partners:
CIMG_09165
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43.
   
 
 0.977
CIMG_05166
Small nucleolar ribonucleoprotein complex subunit.
   
   0.967
CIMG08460
Bystin.
   
   0.965
CIMG_03139
rRNA 2'-O-methyltransferase fibrillarin.
   
   0.964
CIMG_00710
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
   0.956
CIMG_05590
Nuclear protein.
   
   0.953
CIMG_02333
Nucleolin.
   
 
 0.953
CIMG_01035
ATP-dependent RNA helicase.
   
 
 0.951
FAL1
ATP-dependent RNA helicase FAL1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity). Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
   
 
 0.951
CIMG_07254
Uncharacterized protein.
    
 
 0.946
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.