STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity). (1251 aa)    
Predicted Functional Partners:
CIMG_05779
Actin associated protein Wsp1.
   
 
 0.960
CIMG_02413
Calmodulin; Belongs to the calmodulin family.
    
 
 0.939
CIMG_07003
WH2 domain-containing protein.
    
 
 0.889
CIMG_00179
Actin polymerization protein Bzz1.
   
 
 0.829
CIMG_05851
Uncharacterized protein.
    
 
 0.790
CIMG_08162
Calmodulin-beta, variant.
    
 
 0.759
CIMG_09161
Actin cytoskeleton organization protein.
 
  
 
 0.732
CIMG_00965
Fimbrin, variant 1.
   
  
 0.714
CIMG_02791
Actin.
    
 
 0.658
CIMG_05895
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.658
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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