STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOG1Mitogen-activated protein kinase HOG1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (364 aa)    
Predicted Functional Partners:
CIMG_03086
STE/STE7 protein kinase.
  
0.994
CIMG_08522
Protein tyrosine phosphatase.
    
 0.991
CIMG_03698
BZIP transcription factor.
    
 0.987
CIMG_09373
Protein phosphatase 2C.
   
 0.983
CIMG_01739
Stress response transcription factor SrrA/Skn7.
    
 0.928
CIMG_05853
CAMK/CAMKL/GIN4 protein kinase.
  
 
 
0.921
CIMG_04514
CAMK/CAMK1/CAMK1-RCK protein kinase.
  
 
0.905
CIMG_09164
Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily.
     
 0.900
CIMG_01984
Uncharacterized protein.
    
 0.877
CIMG_07638
SRF-type transcription factor RlmA.
    
 0.848
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.