STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA1Metacaspase-1; Involved in cell death (apoptosis). (462 aa)    
Predicted Functional Partners:
CIMG_00821
Endonuclease.
    
 
 0.578
NMA111
Pro-apoptotic serine protease NMA111; Nuclear serine protease which mediates apoptosis. Belongs to the peptidase S1C family.
      
 0.571
CIMG_06686
Bax Inhibitor family protein; Belongs to the BI1 family.
      
 0.550
CIMG_09407
Cell division control protein 48; Belongs to the AAA ATPase family.
    
 
 0.434
CIMG_05096
Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
      
 0.424
CIMG_03687
Vacuolar protease A; Belongs to the peptidase A1 family.
      
 0.400
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.