STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSE1Class E vacuolar protein-sorting machinery protein HSE1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (612 aa)    
Predicted Functional Partners:
CIMG01226
Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
   
0.995
CIMG00568
Polyubiquitin.
    
 0.893
CIMG_07648
Endosome-associated ubiquitin isopeptidase.
    
 0.845
CIMG_00127
Endosomal sorting complex protein.
   
 0.842
CIMG_01227
Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family.
    
 0.805
CIMG_09572
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.750
CIMG_07076
ESCRT-II complex component.
     
 0.736
CIMG_06300
EF hand domain-containing protein.
    
 0.680
CIMG_08661
Vacuolar protein sorting protein.
     
 0.673
CIMG_09143
APSES transcription factor.
   
 
 0.654
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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