STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALM55820.1Hypothetical protein; SMART: helix_turn_helix, mercury resistance; Pfam: MerR HTH family regulatory protein. (132 aa)    
Predicted Functional Partners:
ALM58373.1
SMART: helix_turn_helix, mercury resistance; Pfam: MerR HTH family regulatory protein.
  
     0.770
ALM58327.1
Pfam: MerR HTH family regulatory protein; SMART: helix_turn_helix, mercury resistance.
  
     0.737
ALM55819.1
Hypothetical protein; Pfam: Aldo/keto reductase family.
 
    0.652
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.647
ALM57839.1
Pfam: Bacterial regulatory proteins, tetR family; Pfam: Transcriptional regulator C-terminal region.
  
     0.527
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.497
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
 
 0.497
ALM55824.1
Pfam: Bacterial regulatory proteins, tetR family.
  
     0.472
ALM57632.1
Pfam: PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: mtlA: PTS system, mannitol-specific IIC component; Pfam: Phosphotransferase system, EIIC.
   
    0.437
nanE
N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
   
    0.437
Your Current Organism:
Staphylococcus equorum
NCBI taxonomy Id: 246432
Other names: ATCC 43958, CCUG 30109, CIP 103502, DSM 20674, NCTC 12414, NRRL B-14765, S. equorum, Staphylococcus sp. SR1, strain PA231
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.