STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutHTIGRFAM: hutH: histidine ammonia-lyase; Pfam: Aromatic amino acid lyase. (502 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
TIGRFAM: hutI: imidazolonepropionase; Pfam: Amidohydrolase.
 
  
 0.991
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.934
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.753
hutG
Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
  
 0.730
nnrD
Carbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
     
 0.617
ALM56127.1
Agmatinase; Pfam: Arginase family; Belongs to the arginase family.
 
  
 0.572
ALM57639.1
Pfam: Arginase family; TIGRFAM: rocF_arginase: arginase; PRINTS: Arginase signature; Belongs to the arginase family.
  
  
 0.499
ALM57995.1
PTS glucose transporter subunit IIABC; Pfam: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; Pfam: Phosphotransferase system, EIIC; TIGRFAM: PTBA: PTS system, glucose subfamily, IIA component; TIGRFAM: EIIB_glc: PTS system, glucose-like IIB component; Pfam: phosphotransferase system, EIIB; TIGRFAM: PTS-II-BC-glcB: PTS system, glucose-specific IIBC component.
   
  
 0.410
Your Current Organism:
Staphylococcus equorum
NCBI taxonomy Id: 246432
Other names: ATCC 43958, CCUG 30109, CIP 103502, DSM 20674, NCTC 12414, NRRL B-14765, S. equorum, Staphylococcus sp. SR1, strain PA231
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