STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L8Y8V4_TUPCHRap guanine nucleotide exchange factor 1. (1046 aa)    
Predicted Functional Partners:
CRKL
Crk-like protein.
    
 0.994
GRB2
Growth factor receptor-bound protein 2.
   
 0.872
L9KJB8_TUPCH
Breast cancer anti-estrogen resistance protein 1.
    
 0.862
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.848
RAP1A
Ras-related protein Rap-1A.
    
 0.799
NEDD9
Enhancer of filamentation 1.
    
 0.744
L9KYP5_TUPCH
E3 ubiquitin-protein ligase CBL-B.
    
 0.724
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.714
L9L8I1_TUPCH
GRB2-associated-binding protein 1.
    
 0.678
RHOQ
Rho-related GTP-binding protein RhoQ.
   
 0.658
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.