STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM170BC2H2-type domain-containing protein. (255 aa)    
Predicted Functional Partners:
L9KFK4_TUPCH
Histone H2A deubiquitinase MYSM1.
   
 0.764
ITSN1
Intersectin-1.
    
 0.601
L8XYU9_TUPCH
Dynactin subunit 2.
   
 0.562
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.554
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.545
DCTN5
Dynactin subunit 5.
    
 0.541
L8YAD0_TUPCH
WD repeat-containing protein 1.
   
 0.540
L9KNG3_TUPCH
Dynactin subunit 4.
    
 0.540
L9LCE1_TUPCH
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
   
 0.533
GPBAR1
G-protein coupled bile acid receptor 1.
   
 0.532
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.