node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECSIT | IRAK4 | L8YIA6 | L8Y6J2 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. | Interleukin-1 receptor-associated kinase 4. | 0.553 |
ECSIT | L8YAE7_TUPCH | L8YIA6 | L8YAE7 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. | Toll-interacting protein. | 0.634 |
IL1B | IRAK4 | L9JLW9 | L8Y6J2 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1 receptor-associated kinase 4. | 0.754 |
IL1B | L8YAE7_TUPCH | L9JLW9 | L8YAE7 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Toll-interacting protein. | 0.639 |
IL1B | L8YB37_TUPCH | L9JLW9 | L8YB37 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1 receptor-like 2. | 0.959 |
IL1B | L9JK57_TUPCH | L9JLW9 | L9JK57 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1 receptor accessory protein. | 0.972 |
IL1B | L9KL93_TUPCH | L9JLW9 | L9KL93 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1 receptor-associated kinase-like 2. | 0.735 |
IL1B | L9KW49_TUPCH | L9JLW9 | L9KW49 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1 receptor-associated kinase 3. | 0.471 |
IL1B | L9L6M2_TUPCH | L9JLW9 | L9L6M2 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Toll-like receptor 4. | 0.664 |
IL1B | MYD88 | L9JLW9 | L8Y2R9 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.805 |
IRAK4 | ECSIT | L8Y6J2 | L8YIA6 | Interleukin-1 receptor-associated kinase 4. | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. | 0.553 |
IRAK4 | IL1B | L8Y6J2 | L9JLW9 | Interleukin-1 receptor-associated kinase 4. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.754 |
IRAK4 | L8YAE7_TUPCH | L8Y6J2 | L8YAE7 | Interleukin-1 receptor-associated kinase 4. | Toll-interacting protein. | 0.874 |
IRAK4 | L8YB37_TUPCH | L8Y6J2 | L8YB37 | Interleukin-1 receptor-associated kinase 4. | Interleukin-1 receptor-like 2. | 0.772 |
IRAK4 | L9JK57_TUPCH | L8Y6J2 | L9JK57 | Interleukin-1 receptor-associated kinase 4. | Interleukin-1 receptor accessory protein. | 0.793 |
IRAK4 | L9KL93_TUPCH | L8Y6J2 | L9KL93 | Interleukin-1 receptor-associated kinase 4. | Interleukin-1 receptor-associated kinase-like 2. | 0.978 |
IRAK4 | L9KW49_TUPCH | L8Y6J2 | L9KW49 | Interleukin-1 receptor-associated kinase 4. | Interleukin-1 receptor-associated kinase 3. | 0.747 |
IRAK4 | L9L6M2_TUPCH | L8Y6J2 | L9L6M2 | Interleukin-1 receptor-associated kinase 4. | Toll-like receptor 4. | 0.702 |
IRAK4 | MYD88 | L8Y6J2 | L8Y2R9 | Interleukin-1 receptor-associated kinase 4. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.999 |
L8YAE7_TUPCH | ECSIT | L8YAE7 | L8YIA6 | Toll-interacting protein. | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. | 0.634 |