STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1FMyosin-If; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2492 aa)    
Predicted Functional Partners:
L8Y5X9_TUPCH
Wiskott-Aldrich syndrome protein like protein.
   
 
 0.907
L9KSH4_TUPCH
WAS/WASL-interacting protein family member 1.
    
 
 0.697
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.627
L9LEY9_TUPCH
Elongator complex protein 4.
   
 
 0.595
L9KTU2_TUPCH
Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.
    
 
 0.584
ELP3
Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.
    
 
 0.583
L8Y4Q0_TUPCH
Cdc42-interacting protein 4.
   
 
 0.567
L8YBP2_TUPCH
Formin-binding protein 1.
   
 
 0.567
L9LD51_TUPCH
Formin-binding protein 1-like protein.
   
 
 0.567
UNC45B
Protein unc-45 like protein B.
    
 
 0.553
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.