STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L9JHD4_TUPCHPartitioning defective 3 like protein. (1950 aa)    
Predicted Functional Partners:
PARD6A
Partitioning defective 6 like protein alpha.
    
 0.950
PARD6B
Partitioning defective 6 like protein beta.
    
 0.856
L8YA34_TUPCH
Partitioning defective 6 like protein gamma.
    
 0.848
CDH5
Cadherin-5.
    
 
 0.812
MPP5
MAGUK p55 subfamily member 5; Belongs to the MAGUK family.
    
 0.668
RASSF8
Ras association domain-containing protein 8.
    
 
 0.642
F11R
Junctional adhesion molecule A.
    
 0.619
TGFBR2
TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]
   
  0.577
CASK
Peripheral plasma membrane protein CASK.
    
 0.574
L8Y402_TUPCH
Intraflagellar transport protein 57 like protein.
    
 0.557
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.